Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 CausalMutation disease CLINVAR [Hereditary gastric cancer]. 20824432 2010
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 CausalMutation disease CLINVAR [Hereditary diffuse gastric cancer (HDGC): presentation of a family with a new mutation of the CDH1 gene]. 17955726 2007
Entrez Id: 7372
Gene Symbol: UMPS
UMPS 		0.300 Biomarker disease CTD_human [Clinical and prognostic significance of protein and gene expression of orotate phosphoribosyltransferase in gastric carcinoma]. 16912530 2006
Entrez Id: 30834
Gene Symbol: ZNRD1
ZNRD1 		0.300 Biomarker disease CTD_human ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2. 16609701 2006
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		0.300 Biomarker disease CTD_human Xeroderma pigmentosum group D 751 polymorphism as a predictive factor in resected gastric cancer treated with chemo-radiotherapy. 17009404 2006
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.360 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 1496
Gene Symbol: CTNNA2
CTNNA2 		0.300 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 2737
Gene Symbol: GLI3
GLI3 		0.300 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 54894
Gene Symbol: RNF43
RNF43 		0.300 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 4588
Gene Symbol: MUC6
MUC6 		0.300 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A 		0.300 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 387
Gene Symbol: RHOA
RHOA 		0.300 Biomarker disease CTD_human Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. 24816253 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 GeneticVariation disease BEFREE We used a Markov model of HDGC progression associated with pathogenic variants in CDH1 to simulate outcomes of hypothetical cohorts with different ages at time of PTG (ages 20-79 years). 31220641 2020
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 PosttranslationalModification disease BEFREE We thus examined a series of human eHDGC and detected CDH1 promoter methylation in 50% of foci. 19223545 2009
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 Biomarker disease BEFREE We set out to outline the role of CDH1 in HDGC. 15780560 2005
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 Biomarker disease BEFREE We searched for CDH1 germline defects in 32 HDGC Italian probands selected according to international consensus criteria and in 5 selected relatives. 24493355 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 GeneticVariation disease UNIPROT We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene. 10319582 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 AlteredExpression disease BEFREE We reported recently that a single nucleotide polymorphism (-347 G-->GA) in the E-cadherin promoter suppressed E-cadherin expression and was associated with familial gastric cancer. 15231691 2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 GeneticVariation disease BEFREE We report an asymptomatic patient belonging to a family with hereditary diffuse gastric cancer syndrome with a novel pathogenic mutation in the E-cadherin gene. 22738705 2012
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 GeneticVariation disease BEFREE We recommend genetic counseling and consideration of prophylactic gastrectomy in young, asymptomatic carriers of germ-line truncating CDH1 mutations who belong to families with highly penetrant hereditary diffuse gastric cancer. 11419427 2001
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 GeneticVariation disease BEFREE We present an asymptomatic patient from a HDGC family carrying a novel CDH1 mutation in whom FDG-PET scanning facilitated early detection of HDGC. 15475432 2004
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 GeneticVariation disease BEFREE We investigated the mutation status of the CDH1 gene in 25 Korean EODGC patients younger than 50 years and 23 HDGC patients who met the clinical criteria for HDGC. 23264079 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 CausalMutation disease CLINVAR We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.800 Biomarker disease CTD_human We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428 1999